Compile Data Set for Download or QSAR
Found 296 of affinity data for UniProtKB/TrEMBL: P26433
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381804(US10272079, Compound 161)copy SMILEScopy InChI
Affinity DataIC50: 0.631nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381783(US10272079, Compound 140)copy SMILEScopy InChI
Affinity DataIC50: 1.26nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381691(US10272079, Compound 48 | US10272079, Compound 65)copy SMILEScopy InChI
Affinity DataIC50: 1.41nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381762(US10272079, Compound 119)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381826(US10272079, Compound 003)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB85X0PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381817(US10272079, Compound 174)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381742(US10272079, Compound 99)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381826(US10272079, Compound 003)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381793(US10272079, Compound 150)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM426615(N,N′-(10,17-dioxo-3,6,21,24-tetraoxa-9,11,16...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB85X0PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381791(US10272079, Compound 148)copy SMILEScopy InChI
Affinity DataIC50: 3.98nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381741(US10272079, Compound 98)copy SMILEScopy InChI
Affinity DataIC50: 3.98nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381823(CVD-0019453 | US10272079, Compound 002 | US1027207...)copy SMILEScopy InChI
Affinity DataIC50: 3.98nMAssay Description:The ability of compounds to inhibit Rat NHE3-mediated Na+-dependent H+ antiport after application and washout was measured using a modification of th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381751(US10272079, Compound 108)copy SMILEScopy InChI
Affinity DataIC50: 3.98nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381690(US10272079, Compound 47 | US10272079, Compound 66)copy SMILEScopy InChI
Affinity DataIC50: 4.47nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381648(US10272079, Compound 6)copy SMILEScopy InChI
Affinity DataIC50: 4.47nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381715(US10272079, Compound 72)copy SMILEScopy InChI
Affinity DataIC50: 5.01nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381794(US10272079, Compound 151)copy SMILEScopy InChI
Affinity DataIC50: 5.01nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM50601178(CHEMBL5202545)copy SMILES
Affinity DataIC50: 6.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB85X0PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381815(US10272079, Compound 172)copy SMILEScopy InChI
Affinity DataIC50: 6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381770(US10272079, Compound 127)copy SMILEScopy InChI
Affinity DataIC50: 6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM426616(N,N′-(2,2′-(2,2′-(2,2′-(1,...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB85X0PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381785(US10272079, Compound 142)copy SMILEScopy InChI
Affinity DataIC50: 7.94nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381792(US10272079, Compound 149)copy SMILEScopy InChI
Affinity DataIC50: 7.94nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381743(US10272079, Compound 100)copy SMILEScopy InChI
Affinity DataIC50: 7.94nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381823(CVD-0019453 | US10272079, Compound 002 | US1027207...)copy SMILEScopy InChI
Affinity DataIC50: 9.33nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381710(US10272079, Compound 67)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381678(US10272079, Compound 35)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM50196789(CHEMBL3892788)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of rat NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7CDJPubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM50601180(CHEMBL5170002)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB85X0PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM50601179(CHEMBL5202068)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB85X0PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381823(CVD-0019453 | US10272079, Compound 002 | US1027207...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381822(US10272079, Compound 179)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381684(US10272079, Compound 41)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381806(US10272079, Compound 163)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381724(US10272079, Compound 81)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381677(US10272079, Compound 34)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM50601181(CHEMBL5170188)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB85X0PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM426507(N1,N4-bis(2-(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2...)copy SMILEScopy InChI
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB85X0PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381818(US10272079, Compound 175)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381689(US10272079, Compound 46)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381763(US10272079, Compound 120)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381789(US10272079, Compound 146)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381673(US10272079, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381823(CVD-0019453 | US10272079, Compound 002 | US1027207...)copy SMILEScopy InChI
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB85X0PubMed
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381820(US10272079, Compound 177)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381674(US10272079, Compound 31)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381685(US10272079, Compound 42)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381798(US10272079, Compound 155)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
GlaxoSmithKline

LigandPNGBDBM381800(US10272079, Compound 157)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251MHHUS Patent
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